Th17 Responses Are Not Induced in Dextran Sodium Sulfate Model of Acute Colitis

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Th17 Responses Are Not Induced in Dextran Sodium Sulfate Model of Acute Colitis

Dextran sodium sulfate (DSS) is a widely used chemical model for inflammatory bowel disease (IBD). It is thought that imbalances in the T helper (Th) cell subsets contribute to IBD. Recent studies suggest that the acute DSS-colitis model is polarized toward a Th1/Th17 profile based on RT-PCR analysis of colonic tissues. In the current study we determined whether colonic Th cells from DSS-coliti...

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ژورنال

عنوان ژورنال: Immune Network

سال: 2011

ISSN: 1598-2629,2092-6685

DOI: 10.4110/in.2011.11.6.416